Announcements

If you missed last week’s TEDx “Innovations in Therapeutic Trials, Assessment & Care for Alzheimer’s Disease”, the recording is now available. https://school.wakehealth.edu/Research/Research-Symposium?utm_source=Master+Research+Rundown+%26+Funding&utm_campaign=c56158d709-

American Suicide Prevention Foundation – Focus Grants LOI requests          ASPF research grants support studies that will increase our understanding of suicide or test treatments and other interventions that save lives.          Funding up to $500,000 per year for up to 3 years.          LOI due August 1st          Full info link: https://afsp.org/research-grant-information#section1

IDSA Foundation > Microbial Pathogenesis In Alzheimer’s Disease Grant    Intriguing evidence suggests Alzheimer’s disease may have a link to infectious diseases or a microbial mechanism. The IDSA Foundation established the Alzheimer’s Research Grant now known as the Microbial Pathogenesis in Alzheimer’s Disease Grant, in 2018 to foster further investigation. These grants support research that suggest evidence of an infectious agent or microbial community is correlated to Alzheimer’s disease and promotes novel research in the field of microbial triggers for Alzheimer’s disease.    Funding between $30,000 - $250,000 depending on work experience.    Due date: Tuesday, August 31st    Full info link: https://idsafoundation.org/alz-research-grant/

Pilot, Foundation, NIH Funding Opportunities https://mailchi.mp/wakehealth.edu/8yng942go6-8247818?e=9122ea0f40

Upcoming Events

Cancer Biology Seminar Date/Time:     Tuesday, July 20th (9:00 – 10:00am) Speaker:         Enzo Palma, PhD (Postdoc) Title:                “Preclinical development of a novel drug regimen to condition CD30+ T cell lymphoma prior to CD30-targeted CAR-T cell therapy” Webex:           https://wakehealth.webex.com/wakehealth/j.php?MTID=mcfbbdf13b274693d58ae7eebe8cb0e19 [wakehealth.webex.com]

AVE THE DATE > Mechanistic Basic Science Research Integration Retreat > August 10, 2021       Tuesday, August 10th (1 – 5pm)  > Biotech Atrium and via WebEx       An event to discuss the Wake Forest-Atrium Health Integrative Research Plan for Excellence, promote translational, transformative research across departments and geographical locations, provide opportunities to get to know potential collaborators and identify overarching research themes for focused development.        Followed by a wine and cheese social hour at 5pm       If you plan to attend in person or via WebEx – please contact Robin Newsome rnewsome@wakehealth.edu  ASAP

Recent Publications

Vylet’al P, Kidd K, *Ainsworth HC, Springer D, Vrbacka A, Pnstoupilova A, Hughey RP, Alper SL, Lennon N, Harrison S, Harden M, Robins V, Taylor A, Marting L, Howard k, Bitar I, Langefeld CD, Baresova V, Hartmannova H, Hodanova K, Zima T, Zivna M, Kmoch S, Bleyer AJ. Plasma Mucin-1 (CA16-3) Levels in Autosomal Dominant Tubulointerstitial Kidney Disease due to MUC1 Mutations. Am J Nephrol. 2021 Jun 7;1-10. [Online ahead of print] PMID: 34098564. https://doi.org/10.1159/000515810  

Pu T, Erali RA, Share M, Russell GB, Clark CJ, Levine EA, Shen P. Persistent opioid use after curative-intent hepatectomy for neoplastic disease. J Surg Oncol. 2021 June 22. [Online ahead of print] PMID: 34156105. https://doi.org/10.1002/jso.26472  

Soto-Pantoja DR, Gaber M, Arnone AA, Bronson SM, Cruz-Diaz N, Wilson AS, Clear KYJ, Ramirez MU, Kucera GL, Levine EA, Lelievre SA, Chaboub L, Chiba A, Yadav H, Vidi P-A, Cook KL. Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis. Cancer Res. 2021 Jun 3;canres.2983.2020. [Online ahead of print] PMID: 34083249. https://doi.org/10.1158/0008-5472.can-20-2983  

Milligan C, Atassi N, Babu S, Barohn RJ, Caress JB, Cudkowicz ME, Evora A, Hawkins GA, Wosiski-Kuhn M, Macklin EA, Shefner JM, Simmons Z, Bowser RP, Ladha SS. Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients. Muscle Nerve. 2021 Jun 1. [Online ahead of print] PMID: 34075589. https://doi.org/10.1002/mus.27339  

Wagner VA, Clark KC, Carrillo-Saenz L, Holl KA, Belez-Bermudez M, Simonsen D, Grobe JL, Wang K, Thurman A, Solberg Woods LC, Lehmler H-J, Kwitek AE. Bisphenol F Exposure in Adolescent Heterogeneous Stock Rats Affects Growth and Adiposity. Toxicol Sci. 2021 May 27;181(2):246-261. PMCID: PMC8163043. https://doi.org/10.1093/toxsci/kfab035  

Members NEWS

Dr. Roy E. Strowd had a recent press release by the American Academy of Neurology “Could Ketogenic Diet be Helpful with Brain Cancer?”  “There are not a lot of effective treatments for these types of brain tumors, and survival rates are low, so any new advances are very welcome,” said study author Roy E. Strowd, MD, MS, MEd, of Wake Forest School of Medicine in Winston-Salem, N.C., and a Fellow of the American Academy of Neurology. “These cancer cells rely on glucose, or sugar, to divide and grow. Since the ketogenic diet is low in sugar, the body changes what it uses for energy—instead of carbohydrates, it uses what are called ketones. Normal brain cells can survive on ketones, but the theory is that cancer cells cannot use ketones for energy.” For the full release: https://www.aan.com/PressRoom/Home/PressRelease/4907