Recent Publications of 2021
JANUARY 2021
1. Li W, Cohen MB. TTF-1, napsin A, and CDX2 Co-expression in metastic rectal adenocarcinoma to the lung. Cytopathology. 2021 Jan;32(1):146-148. (Epub 2020 Aug 8) PMID: 32633432. https://doi.org/10.1111/cyt.12884
2. Garland-Kledzik M, Uppal A, Naeini YB, Stern S, Erali R, Scholer AJ, Khader AM, Santamaria-Barria JA, Cummins-Perry K, Zhou Y, Votanopoulos KI, Shen P, Levine EA, Bilchik AJ. Prognostic Impact and Utility of Immunoprofiling in the Selection of Patients with Colorectal Peritoneal Carcinomatosis for Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC). J Gastrointest Surg. 2021 Jan;25(1):233-240. (Epub 2020 Dec 2) PMID: 33269456. https://doi.org/10.1007/s11605-020-04886-y
3. White JD, Indencleef K, Naqvi S, Eller RJ, Hoskens H, Roosenboom J, Lee MK, Li J, Mohammed J, Richmond S, Quillen EE, Norton HL, Feingold E, Swigut T, Marazita ML, Peeters H, Hens G, Shaffer JR, Wysocka J, Walsh S, Weinberg SM, Shriver MD, Claes P. Insights into the genetic architecture of the human face. Nat Genet. 2021 Jan;53(1):45-53. (Epub 2020 Dec 7) PMCID: PMC7796995. https://doi.org/10.1038/s41588-020-00741-7
4. Hurford R, Strowd 3rd RE, Cancer and stroke: A relationship thicker than blood. Neurology. 2021 Jan 26;96(4):143-144. (Epub 2020 Dec 4) PMID: 33277414. https://doi.org/10.1212/wnl.0000000000011263
5. *Mishra SP, Jain S, Taraphder S, Yadav H. New Horizons in Microbiota and Metabolic Health Research. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e1052-e1059. (Epub 2020 Oct) PMCID: PMC7823252.. https://doi.org/10.1210/clinem/dgaa769
6. Teo K, Abeysekera KWM, Adams L, Aigner E, Anstee QM, Banales JM, Banerjee R, Basu P, Berg T, Bhatnagar P, Buch S, Canbay A, Caprio S, Chatterjee A, Ida Chen YD, Chowdhury A, Daly AK, Datz C, de Gracia Hahn D, DiStefano JK, Dong J, Duret A; EU-PNAFLD Investigators, Emdin C, Fairey M, Gerhard GS; GOLD Consortium, Guo X, Hampe J, Hickman M, Heintz L, Hudert C, Hunter H, Kelly M, Kozlitina J, Krawczyk M, Lammert F, Langenberg C, Lavine J, Li L, Lim HK, Loomba R, Luukkonen PK, Melton PE, Mori TA, Palmer ND, Parisinos CA, Pillai SG, Qayyum F, Reichert MC, Romeo S, Rotter JI, Im YR, Santoro N, Schafmayer C, Speliotes EK, Stender S, Stickel F, Still CD, Strnad P, Taylor KD, Tybjærg-Hansen A, Umano GR, Utukuri M, Valenti L, Wagenknecht LE, Wareham NJ, Watanabe RM, Wattacheril J, Yaghootkar H, Yki-Järvinen H, Young KA, Mann JP. rs641738C>T near MBOAT7 is associated with liver fat, ALT, and fibrosis in NAFLD: a meta-analysis. J Hepatol. 2021 Jan;74(1):20-30. PMCID: PMC7755037. https://doi.org/10.1016/j.jhep.2020.08.027
7. Kahali B, Chen Y, Feitosa MF, Bielak LF, O’Connell JR, Musani SK, Hegde Y, Chen Y, Stetson LC, Guo X, Fu Y-P, Smith AV, Ryan KA, Eiriksdottir G, Cohain AT, Allison M, Bakshi A, Bowden DW, et.al, Palmer ND, Speliotes EK. A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial infarction. J Clin Endocrinol Metab. 2021 Jan 23;106(2):372-387. (Epub 2020 Nov 24) PMCID: PMC7823249. https://doi.org/10.1210/clinem/dgaa855
8. Dewi FN, JM Cline. Nonhuman primate model in mammary gland biology and neoplasia research. Lab Anim Res. 2021 Jan5;37(1):3. PMCID: PMC7784333. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7784333/
9. Morales LD, Cromack DT, Tripathy D, Fourcaudot M, Kumar S, Curran JE, Carless M, Goring HHH, Hu SL, Lopez-Alvarenga JC, Garske KM, Pajukanta P, Small KS, Glastonbury CA, Das SK, Langefeld C, Hanson RL, Hsueh W-C, Norton L, Arya R, Mummidi S, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP. Further evidence supporting a potential role for ADH1B in obesity. Sci Rep. 2021 Jan 21;11(1):1932. PMCID: PMC7820614. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7820614/
10. Weaver KE, Klepin HD, Wells BJ, Dressler EV, Winkfield KM, Lamar KS, Avery TP, Pajewski NM, Hundley WG, Johnson A, Davidson EC, Lopetegui M, Foraker RE. Cardiovascular Assessment Tool for Breast Cancer Survivors and Oncology Providers: Usability Study. JMIR Cancer. 2021 Jan 21;7(1):e18396. PMCID: PMC7861995. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7861995/
11. Kumar A, Kim S, Su Y, Sharma M, Kumar P, Singh S, Lee J, Furdui CM, Singh R, Hsu F-C, Kim J, Whitlow CT, Nader MA, Deep G. Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone. EBioMedicine. 2021 Jan ;63:103192. PMCID: PMC7804975. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7804975/
12. Lewis JE, Forshaw TE, Boothman DA, Furdui CM, Kemp ML. Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors. Cell Syst. 2021 Jan 20;12(1):68-81.ell. PMCID: PMC7905848. https://doi.org/10.1016/j.cels.2020.12.001
13. Patil AS, Grotegut CA, Gaikwad NW, Dowden SD, Haas DM. Prediction of neonatal morbidity and very preterm delivery using maternal steroid biomarkers in early gestation. PLoS One. 2021 Jan 6;16(1):e0243585. PMCID: PMC7787372. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7787372/
14. Rajendran S, Obeid JS, Binol H, D’Agostino Jr R, Foley K, Zhang W, Austin P, Brakefield J, Gurcan MN, Topaloglu U. Cloud-Based Federated Learning Implementation Across Medical Centers. JCO Clin Cancer Inform. 2021 Jan;5:1-11. PMID: 33411624. https://doi.org/10.1200/cci.20.00060
15. Chen L, Lu Yingzhou, Wu Chiung-Ting, Clarke R, Yu Guoqiang, Van Eyk JE, Herrington DM, Wang Y. Data-driven detection of subtype-specific differentially expressed genes. Sci Rep. 2021 Jan 11;11(1):332. PMCID: PMC7801594. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7801594/
16. Lenchik L, Barnard R, Boutin RD, Kritchevsky SB, Chen H, Tan J, Cawthon PM, Weaver AA, Hsu F-C. Automated Muscle Measurement on Chest CT Predicts All-Cause Mortality in Older Adults From the National Lung Screening Trial. J Gerontol A Biol Sci Med Sci. 2021 Jan 18;76(2):277-285. PMCID: PMC7812435. https://doi.org/10.1093/gerona/glaa141
17. Heald CJ, Sarma A, Sachs JR, Zapadka ME, Jewett T, Bunch PM. Practical Genetics for the Neuroradiologist: Adding Value in Neurogenetic Disease. Acad Radiol. 2021 Jan 22;S1076-6332(21)00007-6. [Online ahead of print] PMID: 33495073. https://doi.org/10.1016/j.acra.2020.12.021
18. Tyagi A, Sharma S, Wu K, Wu S-Y, Xing F, Liu Y, Zhao D, Deshpande RP, D’Agostino Jr RB, Watabe K. Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung. Nat Commun. 2021 Jan 20;12(1):474. PMCID: PMC7817836. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7817836/
19. Harris KS, Shi L, Foster BM, Mobley ME, Elliott PL, Song CJ, Watabe K, Langefeld CD, Kerr BA. CD117/c-kit defines a prostate CSC-like subpopulation driving progression and TKI resistance. Sci Rep. 2021 Jan 14;11(1):1465. PMCID: PMC7809150. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7809150/
20. Xing F, Zhao D, Wu S-Y, Tyagi A, Wu K, Sharma S, Liu Y, Deshpande R, Wang Y, Cleary J, Miller LD, Chittiboyina AG, Yalamanchili C, Mo Y-Y, Watabe K. Epigenetic and Post-transcriptional modulation of SOS1 can promote breast cancer metastasis through obesity-activated c-Met signaling in African American women. Cancer Res. 2021 Jan 14;canres.4031.2019. [Online ahead of print] PMID: 33446575. https://doi.org/10.1158/0008-5472.can-19-4031
21. Coke LN, Wen H, *Comeau M, Ghanem MH, Shih A, Metz CN, Li W, Langefeld CD, Gregersen PK, Simpfendorfer KR. Arg206Cys substitution in DNASE1L3 causes a defect in DNASE1L3 protein secretion that confers risk of systemic lupus erythematosus. Ann Rheum Dis. 2021 Jan 17;annrheumdis-2020-218818. [Online ahead of print] PMID: 33455918. https://doi.org/10.1136/annrheumdis-2020-218810
22. Steber Cole, Hughes RT, McTyre ER, Soike M, Farris M, Levine BJ, Pasche B, Levine E, Blackstock AW. Cisplatin/5-Fluorouracil (5-FU) Versus Carboplatin/Paclitaxel Chemoradiotherapy as Definitive or Pre-Operative Treatment of Esophageal Cancer. Cureus. 2021 Jan 8;13(1):e12574. PMCID: PMC7870131. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7870131/
23. Simpson FR, Pajewski NM, Beavers KM, Kritchevsky S, McCaffery J, Nicklas BJ, Wing RR, Bertoni A, Ingram F, Ojeranti D, Espeland MA. Does the Impact of Intensive Lifestyle Intervention on Cardiovascular Disease Risk Vary According to Frailty as Measured via Deficit Accumulation? J Gerontol A Biol Sci Med Sci. 2021 Jan 18;76(2):339-345. PMID: 32564066. https://doi.org/10.1093/gerona/glaa153
24. Voorhies K, Sordillo JE, McGeachie M, *Ampleford E, Wang AL, Lasky-Su J, Tantisira K, Dahlin A, Kely RS, Ortega VE, Lutz SM, Wu AC. Age by Single Nucleotide Polymorphism Interactions on Bronchodilator Response in Asthmatics. J Pers Med. 2021 Jan 19;11(1):59. PMCID: PMC7833432. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7833432/
25. Teng T, Shively CA, Li X, Jiang X, Neigh GN, Yin B, Zhang Y, Fan L, Xiang Y, Wang M, Liu X, Qin M, Zhou X, Xie P. Chronic unpredictable mild stress produces depressive-like behavior, hypercortisolemia, and metabolic dysfunction in adolescent cynomolgus monkeys. Transl Psychiatry. 2021 Jan 4;11(1):9. PMCID: PMC7791128. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7791128/
26. McCarthy B, Cudykier A, Singh R, Levi-Polyachenko N, Soker S. Semiconducting polymer nanoparticles for photothermal ablation of colorectal cancer organoids. Sci Rep. 2021 Jan 15;11(1):1532. PMCID: PMC7810691. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7810691/
27. King CP, Tripi JA, Hughson AR, Horvath AP, Lamparelli AC, Holl KL, Chitre AS, Polesskaya O, Ishiwari K, Solberg Woods LC, Palmer AA, Robinson TE, Flagel SB, Meyer PJ. Sensitivity to food and cocaine cues are independent traits in a large sample of heterogeneous stock rats. Sci Rep. 2021 Jan 26;11(1):2223. PMCID: PMC7838206. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7838206/
28. Keele GR, Prokop JW, He H, Holl K, Littrell J, *Deal AW, Kim Y, Kyle PB, Attipoe E, Johnson AC, Uhl KL, Sirpilla OL, Jahanbakhsh S, Robinson M, Levy S, Valdar W, Garrett MR, Solberg Woods LC. Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model. Sci Rep. 2021 Jan 22;11(1):2071. PMCID: PMC7822875. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7822875/
29. Saccon TD, *Nagpal R, Yadav H, Cavalcante MB, de Carvlho Nunes AD, Schneider A, Gesing A, Hughes B, Yousefzadeh M, Tchkonia T, Kirkland JL, Niedernhofer LJ, Robbins PD, Masternak MM. Senolytic combination of Dasatinib and Quercetin alleviates intestinal senescence and inflammation and modulates the gut microbiome in aged mice. J Getontol A Biol Sci Med Sci. 2021 Jan 6;glab002. PMID: 33406219. https://doi.org/10.1093/gerona/glab002
FEBRUARY 2021
30. Marquardt RM, Kim TH, Yoo J-Y, Teasley HE, Fazleabas AT, Young SL, Lessey BA, Arora R, Jeong J-W. Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment. FASEB J. 2021 Feb;35(2):e21209. (Epub 2020 Nov 22) PMID: 33222288. https://doi.org/10.1096/fj.202002178r
31. Lu Z, Rajan SAP, *Song Q, Zhao Y, Wan M, aleman J, *Skardal A, Bishop C, Atala A, Lu B. 3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts. Biomaterials. 2021 Feb;269:120668. (Epub 2021 Jan 8) PMID: 33461059. https://doi.org/10.1016/j.biomaterials.2021.120668
32. Nightingale CL, Sterba KR, McLouth LE, Kent EE, Dressler EV, Dest A, Snavely AC, Adonizio CS, Wojtowicz M, Neuman HB, Kazak AE, Carols RC, Hudson MF, Unger JM, Kamen CS, Weaver KE. Caregiver engagement practices in National Cancer Institute Clinical Oncology Research Program settings: Implications for research to advance the field. Cancer. 2021 Feb 15;127(4):639-647. (Epub 2020 Nov 2) PMCID: PMC7854890. https://doi.org/10.1002/cncr.33296
33. Liu L, Ahmed T, Petty WJ, Grant S, Ruiz J, Lycan TW, Topaloglu U, Chou P-C, Miller LD, Hawkins GA, Alexander-Miller MA, O’Neill SS, Powell BL, D’Agostino Jr. RB, Munden RF, Pasche B, Zhang W. SMARCA4 mutations in KRAS-mutant lung adenocarcinoma: a multi-cohort analysis. Mol Oncol. 2021 Feb;15(2):462-472. (Epub 2020 Dec 17) PMCID: PMC7858279. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7858279/
34. Gadgil MD, Kanaya AM, Sands C, Lewis MR, Kandula NR, Herrington DM. Circulating metabolites and lipids are associated with glycaemic measures in South Asians. Diabet Med. 2021 Feb;38(2):e14494. (Epub 2020 Dec 25) PMID: 33617033. https://doi.org/10.1111/dme.14494
35. Snavely AC, Hendley N, Stopyra JP, Lenoir KM, Wells BJ, Herrington DM, Heistand BC, Miller CD, Mahler SA. Sex and Race Differences in Safety and Effectiveness of the HEART Pathway Accelerated Diagnostic Protocol for Acute Chest Pain: Sex and Race difference in HEART Pathway Outcomes. Am Heart J. 2021 Feb;232:125-136. (Epub 2020 Nov 6) PMID: 33160945. https://doi.org/10.1016/j.ahj.2020.11.005
36. Lenaerts L, Reynhout S, Verbinnen I, Laumonnier F, Toutain A, Bonnet-Brilhault F, Hoorne Y, Joss S, Chassevent AK, Smith-Hicks C, Loeys B, Joset P, Steindl K, Rauch A, Mehta SG, Chung WK, Devriendt K, Holder SE, Jewett T, Baldwin LM, Wilson WG, Towner S, Srivastava S, Johnson HF, Daumer-Haas C, Baethmann M, Ruiz A, Gabau E, Jain V, Varghese V, Al-Beshri A, Fulton S, Wechsberg O, Orenstein N, Prescott K, Childs A-M, Faivre L, Moutton S, Sullivan JA, Shashi V, Koudijs SM, Heijligers M, Kivuva E, McTague A, Male A, Ierland Yv, plecko B, Maystadt I, Hamid R, Hannig VL, Houge G, Janssens V. The broad phenotypic spectrum of PPP2R1A-related neurodevelopmental disorders correlates with the degree of biochemical dysfunction. Genet Med. 2021 Feb;23(2):352-362. (Epub 2020 Oct 27) PMCID: PMC7862067. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7862067/
37. Chouliaras K, Patel N, Senehi R, Ethun CG, Poultsides G, Grignol V, Gamblin TC, Roggin KK, Fields RC, D’Agostino Jr R, Levine EA, Cardona K, Votanopoulos K. Impact of resection margin on outcomes in high-grade soft tissue sarcomas of the extremity-A USSC analysis. J Surg Oncol. 2021 Feb;123(2):479-488. (Epub 2020 Nov 4) PMID: 33150594. https://doi.org/10.1002/jso.26275
38. *Sharma S, Pei X, Xing F, *Wu S-Y, *Wu K, *Tyagi A, *Zhao D, Deshpande R, Ruiz MG, Singh R, Lyu F, Watabe K. Regucalcin promotes dormancy of prostate cancer. Oncogene. 2021 Feb;40(5):1012-1026. (Epub 2020 Dec 15) PMID: 33323968. https://doi.org/10.1038/s41388-020-01565-9
39. Rodrigues ACZ, Wang Z-M, Messi ML, Bonilla HJ, Liu L, Freeman WM, Delbono O. Heart and neural crest derivative 2-induced preservation of sympathetic neurons attenuates sarcopenia with aging. J Cachexia Sarcopenia Muscle. 2021 Feb;12(1):91-108. (Epub 2020 Nov 30) PMCID: PMC7890150. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7890150/
40. Pei Y, Otieno D, Gu I, Lee S-O, Parks JS, Schimmel K, Kang HW. Effect of quercetin on nonshivering thermogenesis of brown adipose tissue in high-fat diet-induced obese mice. J Nutr Biochem. 2021 Feb;88:108532. (Epub 2020 Oct 29) PMID: 33130188. https://doi.org/10.1016/j.jnutbio.2020.108532
41. Labeau SO, Afonso E, Benbenishty J, Blackwood B, Boulanger C, brett SJ, Calvino-Gunther S, Chaboyer W, Coyer F, Deschepper M, Francois G, Honore PM, Jankovic R, Khanna AK, Llaurado-Serra M, Lin F, Rose L, Rubulotta F, Saager L, Williams G, Blot SI, DecubICUs Study Team; European Society of Intensive Care Medicine (ESICM) Trials Group Collaborators (*Zhang W). Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study. Intensive Care Med. 2021 Feb;47(2):160-169. (Epub 2020 Oct 9) PMCID: PMC7880913. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7880913/
42. Wilson HL, D’Agostino Jr RB, Meegalla N, Petro R, Commander S, Topaloglu U, Zhang W, Porosnicu M. The Prognostic and Therapeutic Value of the Mutational Profile of Blood and Tumor Tissue in Head and Neck Squamous Cell Carcinoma. Oncologist. 2021 Feb;26(2):e279-e289. (Epub 2020 Nov 20) PMCID: PMC7873320. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7873320/
43. Chen VL, Du X, Chen Y, Kuppa A, Handelman SK, Vohnoutka RB, Peyser PA, Palmer ND, Bielak LF, Halligan B, Speliotes EK. Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology. Nat Commun. 2021 Feb 5;12(1):816. PMCID: PMC7865025 http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7865025/
44. Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, et.al, Bowden DW, et.al, Palmer ND, et.al. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 Feb;590(7845):290-299. PMCID: PMC7875770. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7875770/
45. Mainali R, Zabalawi M, Long D, Buechler N, Quillen E, Key C-C, Zhu X, Parks JS, Furdui C, Stacpoole PW, Martinez J, McCall CE, Quinn MA. Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction. Elife. 2021 Feb 22;10:e64611. PMCID: PMC7901874. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7901874/
46. *Ruggiero AD, Key CCC, Kavanagh K. Adipose Tissue Macrophage Polarization in Healthy and Unhealthy Obesity. Front Nutr. 2021 Feb 17;8:625331. PMCID: PMC7925825. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7925825/
47. Jones MA, MacCuaig WM, Frickenstein AN, Camalan S, Gurcan MN, Holter-Chakrabarty J, Morris KT, McNally MW, Booth KK, Carter S, Grizzle WE, McNally LR. Molecular Imaging of Inflammatory Disease. Biomedicines. 2021 Feb 4;9(2):152. PMCID: PMC7914540. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7914540/
48. Blumhagen RZ, Schwartz DA, Langefeld CD, Fingerlin TE. Identification of Influential Variants in Significant Aggregate Rare Variant Tests. Hum Hered. 2021 Feb 10;1-13. [Online ahead of print] PMID: 33567433. https://doi.org/10.1159/000513290
49. Zimmerman KD, Espeland MA, Langefeld CD. A practical solution to pseudoreplication bias in single-cell studies. Nat Commun. 2021 Feb 2;12(1):738. PMCID: PMC7854630. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7854630/
50. Schulson L, Lin M-Y, Paasche-Orlow MK, Hanchate AD. Limited English Proficient patient Visits and Emergency Department Admission Rates for Ambulatory Care Sensitive Conditions in California: A Retrospective Cohort Study. J Gen Intern Med. 2021 Feb 2. [Online ahead of print] PMID: 33528781. https://doi.org/10.1007/s11606-020-06523-5
51. Yoo KM, Murphy SV, *Skardal A. A Rapid Corosslinkable Maleimide-Modified Hyaluronic Acid and Gelatin Hydrogel Delivery System for Regenerative Applications. Gels. 2021 Feb 1;7(1):13. PMCID: PMC33631359. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7931058/
52. Messier SP, Mihalko SL, Beavers DP, Nicklas BJ, DeVita P, Carr JJ, Hunter DJ, Lyles M, Guermazi A, Bennell KL, Loeser RF. Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults with Knee Osteoarthritis: The START Randomized Clinical Trial. JAMA. 2021 Feb 16;325(7):646-657. PMCID: PMC7887656. https://doi.org/10.1001/jama.2021.0411
53. Opron K, Begley LA, Erb-Downward JR, Freeman C, Madapoosi S, Alexis NE, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Christenson SA, Comelias AP, Cooper CB, Couper DJ, Doerschuk CM, Dransfield MT, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kaner RJ, Krishnan J, O’Neal WK, Ortega VE, et.al. Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort. NPJ Biofilms Microbiomes. 2021 Feb 5;7(1):14. PMCID: PMC7865064. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7865064/
54. Fortis S, Comelias A, Bhatt SP, Hoffman EA, Han MK, Bhakta NR, Paine 3rd R, Ronish B, Kanner RE, Dransfield M, Hoesterey D, Buhr RG, Barr RG, Dolezal B, Ortega VE, et. al. Ratio of Forced Expiratory Volume in 1 second/Slow Vital Capacity (FEV1/SVC)<0.7 is associated with clinical, functional, and radiologic features of obstructive lung disease in smokers with preserved lung function. Chest. 2021 Feb 1;S0012-3692(21)00229-4. [Online ahead of print] PMID: 33539837. https://doi.org/10.1016/j.chest.2021.01.067
55. Clougherty JE, Kinnee EJ, Cardet JC, Mauger D, Bacharier L, Beigelman A, Blake KV, Cabana MD, Castro M, Chmiel JF, Covar R, Fitzpatrick A, Gaffin JM, Gentile D, Israel E, Jackson Dj, Kraft M, Krishnan JA, Kumar HV, Lang JE, Lazarus SC, Lemanske Jr RF, Lima J, Martinez FD, Morgan W, Moy J, Myers R, Naureckas ET, Ortega VE, et, al. Geography, generalizability, and susceptibility in clinical trials. 2021 Feb 1;S2213-2600(21)00046-1. [Online ahead of print] PMID: 33539731. https://doi.org/10.1016/s2213-2600(21)00046-1
56. Teng T, Shively CA, Li X, Jiang X, Neigh GN, Yin B, Zhang Y, Fan L, Xiang Y, Wang M, Liu X, Qin M, Zhou X, Xie P. Correction to: Chronic unpredictable mild stress produces depressive-like behavior, hypercortisolemia, and metabolic dysfunction in adolescent cynomolgus monkeys. Transl Psychiatry. 2021 Feb 15;11(1):126. PMCID: PMC7884687. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7884687/ 7810691
57. Weber GM, Houng C, Palmer NP, Avillach P, Murphy SN, Gutierrez-Sacristan A, Xia Z, Serret-larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann KG, South AM, et, al. International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study. medRxiv. 2021 Feb 5;2020.12.16.20247684. (Preprint) PMCID: PMC7872369. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7872369/
58. *Miller B, Mainali R, *Nagpal R, Yadav H. A Newly Developed Synbiotic Yogurt Prevents Diabetes by Improving the Microbiome-Intestine-Pancreas Axis. Int J Mol Sci. 2021 Feb 6;22(4):1647. PMCID: PMC7915949. https://doi.org/10.3390/ijms22041647
59. Labeau SO, Afonso E, Benbenishty J, Blackwood B, Boulanger C, brett SJ, Calvino-Gunther S, Chaboyer W, Coyer F, Deschepper M, Francois G, Honore PM, Jankovic R, Khanna AK, Llaurado-Serra M, Lin F, Rose L, Rubulotta F, Saager L, Williams G, Blot SI, DecubICUs Study Team; European Society of Intensive Care Medicine (ESICM) Trials Group Collaborators (*Zhang W). Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study. Intensive Care Med. 2021 Feb 26. [Online ahead of print] PMID: 33635356. https://doi.org/10.1007/s00134-020-06327-5
MARCH 2021
60. Mekky G, Seeds M, Diab A E-AA, Shehata AM, Ahmed-Farid O A-H, Alzebdeh D, Bishop C, Atala A. The potential toxic effects of magnesium oxide nanoparticles and valproate on liver tissue. J Biochem Mol Toxicol. 2021 Mar;35(3):e22676. (Epub 2020 Dec 14) PMID: 33315275. https://doi.org/10.1002/jbt.22676
61. Sun L, Zhang X, *Song Q, Liu L, *Forbes E, Tian W, Zhang Z, Kang Y, Wang H, Flemming JB, Pasche BC, Zhang W. IGFBP2 promotes tumor progression by inducing alternative polarization of macrophages in pancreatic ductal adenocarcinoma through the STAT3 pathway. Cancer Lett. 2021 Mar 1;500:132-146. (Epub 2020 Dec 10) PMCID: PMC7923838. https://doi.org/10.1016/j.canlet.2020.12.008
62. Conley CEW, Mattacola CG, Jochimsen KN, Dressler EV, Lattermann C, Howard JS. A Comparison of Neuromuscular Electrical Stimulation Parameters for Postoperative Quadriceps Strength in Patients After Knee Surgery: A Systematic Review. Sports Health. 2021 Mar;13(2):116-127. (Epub 2021 Jan 11) PMID: 33428557. https://doi.org/10.1177/1941738120964817
63. Gmeiner WH, Dominijanni A, Haber AO, Ghiraldeli LP, Caudell DL, D’Agostino R, Pasche BC, Smith TL, Deng Z, Kiren S, Mani C, Palle K, Brody JR. Inproved anti-Tumor Activity of the Fluoropyrimidine Polymer CF10 in pre-Clinical Colorectal Cancer Models thru Distinct Mechanistic and Pharamcological Properties. Mol Cancer Ter. 2021 Mar;20(3):553-563. (Epub 2020 Dec 23.) PMID: 33361273. https://doi.org/10.1158/1535-7163.mct-20-0516
64. *Ruggiero AD, Davis A, Sherrill C, Westwood B, Hawkins GA, Palmer ND, Chou JW, Reeves T, Cox LA, Kavanagh K. Skeletal Muscle Extracellular Matrix Remodeling with Worsening Glycemic Control in Nonhuman Primates. Am J Physiol Regul Integr Comp Physiol. 2021 Mar 1;320(3):R226-R235. (Epub 2020 Nov 18.) PMCID: PMC7988770.. https://doi.org/10.1152/ajpregu.00240.2020
65. Asthana A, Tamburrini R, Chaimov D, Gazia C, Walker SJ, Van Dyke M, Tomei A, Lablanche S, Robertson J, Opara EC, Soker S, Orlando G. Comprehensive Characterization of the Human Pancreatic Proteome for Bioengineering Applications. Biomaterials. 2021 Mar;270:120613. (Epub 2020 Dec 16) PMID: 33561625. https://doi.org/10.1016/j.biomaterials.2020.120613
66. Turell L, Steglich M, Torres MJ, Deambrosi M, Antmann L, Furdui CM, Schopfer FJ, Alvarez B. Sulfenic acid in human serum albumin: Reaction with thiols, oxidation and spontaneous decay. Free Radic Biol Med. 2021 Mar;165:254-264. (Epub 2021 Jan 28) PMID: 33515755. https://doi.org/10.1016/j.freeradbiomed.2021.01.039
67. Schipper S, Wu H, Furdui CM, Poole LB, Delahunty CM, Park R, Yates 3rd JR, Becker K, Przyborski JM. Indentification of sulfenylation patterns in trophozoite stage Plasmodium falciparum using a non-dimedone based probe. Mol Biochem Parasitol. 2021 Mar;242:111362. (Epub 2021 Jan 26) PMID: 33513391. https://doi.org/10.1016/j.molbiopara.2021.111362
68. * Deal A, Cooper N, Kirse HA, Uneri A, Raab-Graham K, Weiner JL, Solberg Woods LC. Early life stress induces hyperactivity but not increased anxiety-like behavior or ethanol drinking in outbred heterogeneous stock rats. Alcohol. 2021 Mar;91:41-51. (Epub 2020 Dec 13) PMID: 33321179. https://doi.org/10.1016/j.alcohol.2020.11.007
69. Chappell MC, Pirro NT, South AM, Gwathmey TM. Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin-(1-7) and Angiotensin II in Human Plasma. Hypertension. 2021 Mar 3;77(3):e29-e31. (Epub 2021 Jan 5) PMCID: PMC7878344. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7878344/
70. Minen MT, Szperka CL, Cartwright MS, Wells RE. Building the Neurology Pipeline with Undergraduate Students in Research and Clinical Practice. Neurology. 2021 Mar 2;96(9):430-438. (Epub 2020 Dec 8) PMID: 33293387. https://doi.org/10.1212/wnl.0000000000011351
71. Kusamura S, Barretta F, Yonemura Y, Sugarbaker PH, Moran BJ, Levine EA, Goere D, Baratti D, Nizri E, Morris DL, Glehen O, Sardi A, Barrios P, Quenet F, Villeneuve L, Gomez-Portilla A, de Hingh I, Ceelen W, Pelz JOW, Piso P, Gonzalez-Moreno S, Speeten KVD, Deraco M, Peritoneal Surface Oncology Group International (PSOGI) and the French National Registry of Rare peritoneal Surface Malignancies (RENAPE). The Role of Hyperthermic Intraperitoneal Chemotherapy in Pseudomyxoma Peritonei After Cytoreductive Surgery. JAMA Surg. 2021 Mar 1;156(3):e206363. PMCID: PMC7841579. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7841579/
72. Trevisan B, Morsi A, Aleman J, Rodriguez M, Shields J, Meares D, Farland AM, Doering CB, Spencer HT, Atala A, Skardal A, Porada CD, Almeida-Porada G. Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A. Front Bioeng Biotechnol. 2021 Mar 1;9:639070. PMCID: PMC7957060. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7957060/
73. Rossmeisl JH, Herpai D, Quigley M, Cecere TE, Robertson JL, D’Agostino RB, Hinckley J, Tatter SB, Dickinson PJ, Debinski W. Phase I trial of convection-enhanced delivery of IL13RA2 and EPHA2 receptor targeted cytotoxins in dogs with spontaneous intracranial gliomas. Neuro Oncol. 2021 Mar 25;23(3):422-434. PMCID: PMC7992889. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7992889/
74. Holmila R, Wu H, Lee J, Tsang AW, Singh R, Furdui CM. Integrated Redox Proteomic Analysis Highlights New Mechanisms of Sensitivity to Silver Nanoparticles. Mol Cell Proteomics. 2021 Mar 20;100073. [Online ahead of print] PMID: 33757833. https://doi.org/10.1016/j.mcpro.2021.100073
75. Gmeiner WH. Recent Advances in Our Knowledge of mCRC Tumor Biology and Genetics: A Focus on Targeted Therapy Development. Onco Targets Ther. 2021 Mar 25;14:2121-2130. PMCID: PMC8007558. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8007558/
76. Camalan S, Mahmood H, Binol H, Araujo ALD, Santos-Silva AR, Vargas PA, Lopes MA, Khurram SA, Gurcan MN. Convolutional Neural Network-Based Clinical Predictors of Oral Dysplasia: Class Activation Map Analysis of Deep Learning Results. Cancers (Basel). 2021 Mar 14;13(6):1291. PMCID: PMC8001078. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8001078/
77. Akenroye AT, Brunetti T, Romero K, Daya M, Kanchan K, Shankar G, Chavan S, Boorgula M, *Ampleford EA, fonseca HF, Hawkins GA, Teixeira HMP, Campbell M, Rafaels N, Winters A, Bleecker ER, Cruz AA, Barreto ML, Meyers DA, Ortega VA, Figueiredo CA, Barnes KC, Checkley W, Hansel NN, Mathias R. Genome-wide Association study of Asthma, Total IgE, and Lung function in a Cohort of Peruvian Children. J Allergy Clin Immunol. 2021 Mar 10;S0091-6749(21)00366-3. [Online ahead of print] PMID: 33713768. https://doi.org/10.1016/j.jaci.2021.02.035
78. Aladin AI, Soliman EZ, Kitzman DW, Dardari Z, Rasool SH, Yeboah J, Budoff MJ, Psaty BM, Ouyang P, Polak JF, Blumenthal RS, McEvoy JW, Gandhi SK, Herrington DM. Comparison of the Relation of Carotid Intima-Media Thickness with Incident Heart Failure with Reduced Versus Preserved Ejection Fraction (From the Multi-Ethnic Study of Atherosclerosis [MESA]). Am J Cardiol. 2021 Mar 3;S0002-9149(21)00195-8. [Online ahead of print] PMID: 33667446. https://doi.org/10.1016/j.amjcard.2021.02.020
79. Garg PK, Bartz TM, Burke G, Gottdiener JS, Herrington D, Heckbert SR, Kizer JR, Sotoodehnia N, Mukamal KJ. Brachial Flow-Mediated Dilation and Risk of Atrial Fibrillation in Older Adults: the Cardiovascular Health Study. Vasc Health Risk Manag. 2021 Mar 11;17:95-102. PMCID: PMC7961139. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7961139/
80. Armstrong NMD, Spragley KJ, Chen W-M, Hsu F-C. Brewer MS, Horn PJ, Williams SR, Sale MM, Worrall BB, Keene KL. Multi-omic analysis of stroke recurrence in African Americans from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial. PLoS One. 2021 Mar 4;16(3):e0247257. PMCID: PMC7932724. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7932724/
81. Hostetler ZS, Hsu F-C, Barnard R, Jones DA, Davis ML, Weaver AA, Gayzik FS. Injury risk curves in far-side lateral motor vehicle crashes by AIS level, body region and injury code. Traffic Inj Prev. 2021 Mar 12;1-10. [Online ahead of print] PMID: 33709842. https://doi.org/10.1080/15389588.2021.1880006
82. Lin M-Y, Hanchate AD, Frakt AB, Burgess JF Jr, Carey K. Do accountable care organizations differ according to physician-hospital integration?: A retrospective observational study. Medicine (Baltimore). 2021 Mar 26;100(12):e25231. PMID: 33761713. https://doi.org/10.1097/md.0000000000025231
83. Banerjee S, Paasche-Orlow MK, McCormick D, Lin M-Y, Hanchate AD. Association between Medicare’s Hospital Readmission Reduction Program and readmission rates across hospitals by medicare bed share. BMC Health Serv Res. 2021 Mar 19;21(1):248. PMCID: PMC7980319. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7980319/
84. Melendez GC. CMR-Derived Regional Strain and Radiation-Induced Cardiotoxicity: The Importance of Myocardial Inflammation. JACC CardioOncol. 2021 Mar 16;3(1):131-133. PMCID: PMC8352243. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8352243/
85. Sah E, Krishnamurthy S, Ahmidouch MY, Gillispie GJ, Milligan C, Orr ME. The Cellular Senescence Stress Response in Post-Mitotic Brain Cells: Cell Survival at the Expense of Tissue Degeneration. Life (Basel). 2021 Mar 11;11(3):229. PMCID: PMC7998276. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7998276/
86. Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleeker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O’Neal WK, Ortega VE, et, al. PrecISE: Precision Medicine in Severe Asthma An Adaptive Platform Trial with Biomarker Ascertainment. J Allergy Clin Immunol. 2021 Mar 2;S0091-6749(21)003523. [Online ahead of print] PMID: 33667479. https://doi.org/10.1016/j.jaci.2021.01.037
87. Zein JG, McManus JM, Sharifi N, Erzurum SC, Marozkina N, Lahm T, Giddings O, Davis MD, DeBoer MD, Comhair SA, Bazeley P, Kim HJ, Busse W, Calhoun W, Castro M, Chung KF, Fahy JV, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Ortega VE, Peters M, Bleecker ER, Meyers DA, Zhao Y, Wenzel SE, Gaston B. Benefits of Airway Androgen Receptor Expression in Human Asthma. Am J Respir Crit Care Med. 2021 Mar 29. [Online ahead of print] PMID: 33779531. https://doi.org/10.1164/rccm.202009-3720oc
88. Gillenwater LA, Kechris KJ, Pratte KA, Reisdorph N, Petrache I, Labaki WW, O’Neal W, Krishnan JA, Ortega VE, DeMeo DL, Bowler RP. Metabolomic Profiling Reveals Sex Specific Associations with Chronic Obstructive Pulmonary Disease and Emphysema. Metabolites. 2021 Mar 11;11(3):161. PMCID: PMC7999201. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7999201/
89. Kohane IS, Aronow BJ, Avillach P, Beaulieu-Jones BK, Beliazzi R, Bradford RL, Brat GA, Cannataro M, Cimino JJ, Garcia-Barrio N, Gehlenborg N, Ghassemi M, Gutierrez-Sacistan A, Hanauer DA, Holmes JH, Hong C, Klann JG, Loh NHW, Luo Y, Mandl KD, Mohamad D, Moore JH, Murphy SN, Nueraz A, Ngiam KY, Omenn GS, Palmer N, Patel LP, Pedrera-Jimenez M, Sliz P, South AM, et, al. What Every Reader Should Know about Studies Using Electronic Health Record Data but May be Afraid to Ask. J Med Internet Res. 2021 Mar 2;23(3):e22219. PMCID: PMC7927948. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7927948/
90. Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz j, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, Pasche B, Debinski W, Watabe K, Lo H-W. Correction: TGLI1 transcription factor medicates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment. Oncogene. 2021 Mar;40(12):2338. PMID: 33654200. https://doi.org/10.1038/s41388-020-01620-5
91. Wu S-Y, *Sharma S, Wu K, *Tyagi A, *Zhao D, Deshpande RP, Watabe K. Tamoxifen suppresses brain metastasis of estrogen receptor-deficient breast cancer by skewing microglia polarization and enhancing their immune functions. Breast Cancer Res. 2021 Mar 18;23(1):35. PMCID: PMC7977276. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7977276/
92. Wells RE, O’Connell N, Pierce CR, Estave P, Penzien DB, Loder E, Zeidan F, Houle TT. Effectiveness of Mindfulness Meditation vs Headache Education for Adults with Migraine: A Randomized Clinical Trial. JAMA Intern Med. 2021 Mar 1;181(3):317-328. PMCID: PMC7737157. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7737157/
APRIL 2021
93. Cohen JB, McGowan LD, Jensen ET, Rigdon J, South AM. Evaluating sources of bias in observational studies of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker use during COVID-19: beyond confounding. J Hypertens. 2021 Apr 1;39(4):795-805. (Epub 2020 Nov 11) PMID: 33186321. https://doi.org/10.1097/hjh.0000000000002706
94. Graff M, Justice AE, Young KL, Marouli E, Zhang X, Fine RS, Lim E, Buchanan V, Rand K, Feitosa MF, Wojczynski MK, Yanek LR, Shao Y, Rohde R, Adeyemo AA, Aldrich MC, Allison MA, Ambrosone CB, Ambs S, Amos C, Arnett DK, Atwood L, Bandera EV, Bartz T, Becker DM, Berndt SI, Berstein L, Bielak LF, Blot WJ, Bottinger EP, Bowden DW, Bradfield JP, Brody JA, Broeckel U, Burke G, Cade BE, Cai Q, Caporaso N, Carlson C, Carpten J, Casey G, Chanock SJ, Chen G, Chen M, Chen Y-D I, Chen w-M, Chesi A, Chiang CWK, Chu L, Coetzee GA, Conti DV, Cooper RS, Cushman M, Demerath E, Deming SL, *Dimitrov L, Ding J, Diver WR, Duan Q, Evans MK, Falusi AG, Faul JD, Fornage M, Fox C, Freedman BI, Garcia M, Gillanders EM, Goodman P, Gottesman O, Grant SFA, Guo X, Hakonarson H, Haritunians T, Harris TB, Harris CC, Henderson BE, Hennis A, Hernandez DG, Hirschhorn JN, McNeil LH, Howard TD, Howard B, Hsing AW, Hsu Y-H H, Hu JJ, Huff CD, Huo D, Ingles SA, Irvin MR, John EM, Johnson KC, Jordan JM, Kabagambe EK, Kang SJ, Kardia SL, Keating BJ, Kittles RA, Klein EA, Kolb S, Kolonel LN, Kooperberg C, Kuller L, Kutlar A, Lange L, Langefeld CD, Marchand LL, Leonard H, Lettre G, Levin AM, Li Y, Li J, Liu Y, Liu Y, Liu S, Lohman K, Lotay V, Lu Y, Maixner W, Manson JE, McKnight B, Meng Y, Monda KL, Monroe K, Moore JH, Mosley TH, Mudgal P, Murphy AB, Nadukuru R, Nalls MA, Nathanson KL, Nayak U, N’Diaye A, Nemesure B, Neslund-Dudas C, Neuhouser ML, Nyante S, Ochs-Balcom H, Ogundiran TO, Ogunniyi A, Ojengbede O, Okut H, Olopade OI, Olshan A, Padhukasahasram B, Palmer J, Palmer CD, Palmer ND, et al. Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Am J Hum Genet. 2021 Apr 1;108(4):564-582. (Epub 2021 Mar 12) PMCID: PMC8059339. https://doi.org/10.1016/j.ajhg.2021.02.011
95. Collins JA, Kapustina M, Bolduc JA, Pike JFW, Diekman BO, Mix K, Chubinskaya S, Eroglu E, Michel T, Poole LB, Furdui CM, Loeser RF. Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes. Free Radic Biol Med. 2021 Apr;166:90-103. (Epub 2021 Feb 16) PMCID: PMC8009856. https://doi.org/10.1016/j.freeradbiomed.2021.01.054
96. Yang W, Zhou X, Wang X, Lee J, Wu D, Sun P, Furdui CM, Ma T. Protein expression alteration in hippocampus upon genetic repression of AMPKa isoforms. Hippocampus. 2021 Apr;31(4):353-361. (Epub 2021 Jan 25) PMID: 33492732. https://doi.org/10.1002/hipo.23305
97. Gibbs K, Chuang Key C-C, Belfied L, Krall J, Purcell L, Liu C, Files DC. Aging Influences the Metabolic and Inflammatory Phenotype in an Experimental Mouse Model of Acute Lung Injury. J Gerontol A Biol Sci Med Sci. 2021 Apr 30;76(5):770-777. (Epub 2020 Sep 30) PMCID: PMC8087268.. https://doi.org/10.1093/gerona/glaa248
98. Haber AO, Jain A, Mani C, Nevler A, Agostini LC, Golan T, Palle K, Yeo CJ, Gmeiner WH, Brody JR. AraC-FdUMP[10] (CF10) is a next generation fluoropyrimidine with potent antitumor activity in PDAC and synergy with PARG inhibition. Mol Cancer Res. 2021 Apr;19(4):565-572. (Epub 2021 Feb 16) PMID: 33593942. https://doi.org/10.1158/1541-7786.mcr-20-0985
99. Luo S, Clarke SLN, Ramanan AV, Thompson SD, Langefeld CD, *Marion MC, Grom AA, Schooling CM, Gaunt TR, Yeung SLA, Zheng J. Platelet Glycoprotein Ib a-Chain as a Putative Therapeutic Target for Juvenile Idiopathic Arthritis: A Mendelian Randomization Study. Arthritis Rheumatol. 2021 Apr;73(4):693-701. (Epub 2021 Feb 21) PMCID: PMC8005488. https://doi.org/10.1002/art.41561
100. Kim HI, Kim TH, Yoo J-Y, Young SL, Lessey BA, Ku BJ, Jeong J-W. ARID1A and PGR proteins interact in the endometrium and reveal a positive correlation in endometriosis. Biochem Biophys Res Commun. 2021 Apr 23;550:151-157. (Epub 2021 Mar 9). PMCID; PMC8005488. https://doi.org/10.1016/j.bbrc.2021.02.144
101. Rejeski JJ, Fanning J, Nicklas BJ, Rejeski WJ. Six-month changes in ghrelin and glucagon-like peptide-1 with weight loss are unrelated to long-term weight regain in obese older adults. Int J Obes (Lond). 2021 Apr;45(4):888-894. (Epub 2021 Feb 1) PMCID: PMC8005376. https://doi.org/10.1038/s41366-021-00754-0
102. Dunican EM, Elicker BM, Henry T, Gierada DS, Schiebler ML, Anderson W, Barjaktarevic I, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Christenson SA, Comellas A, Cooper CB, Couper D, Criner GJ, Dransfield M, Doerschuk CM, Drummond MB, Hansel NN, Han MK, Hastie AT, Hoffman EA, Krishnan JA, Lazarus SC, Martinez FJ, McCulloch CE, O’Neal WK, Ortega VE, Paine 3rd R, Peters S, Schroeder JD, Woodruff PG, Fahy JV. Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers. Am J Respir Crit Care Med. 2021 Apr 15;203(8):957-968. (Epub 2020 Nov 12). PMCID: PMC8048745. https://doi.org/10.1164/rccm.202006-2248oc
103. Ejike CO, Woo H, Galiatsatos P, Paulin LM, Krishnan JA, Cooper CB, Couper DJ, Kanner RE, Bowler RP, Hoffman EA, Comellas AP, Criner GJ, Barr RG, Martinez FJ, Han MK, Martinez CH, Ortega VE, parekh TM, Christenson SA, Thakur N, Baugh A, Belz DC, Raju S, Gassett AJ, Kaufman JD, Putcha N, Hansel NN. Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes. Am J Respir Crit Care Med. 2021 Apr 15;203(8):987-997. (Epub 2020 Oct 2) PMCID: PMC8048743. https://doi.org/10.1164/rccm.202002-0253oc
104. Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpelainen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, et al. Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Mol Psychiatry. 2021 Apr 15. [Online ahead of print] PMID: 33859359. https://doi.org/10.1038/s41380-021-01087-0
105. Palmer ND, Kahali B, Kuppa A, Chen Y, Du X, Feitosa MF, Bielak LF, O’Connell JR, Musani SK, Guo X, Smith AV, Ryan KA, Eirksdottir G, Allison MA, Bowden DW, Budoff MJ, Carr JJ, Chen Y-DI, Taylor KD, Correa A, Crudup BF, Halligan B, Yang J, Kardia SLR, Launer LJ, Fu Y-P, Mosley TH, Norris JM, Terry JG, O’Donnell CJ, Rotter JI, Wagenknecht LE, Gudnason V, Province MA, Peyser PA, Speliotes EK. Allele Specific Variation at APOE Increases Non-alcoholic Fatty Liver Disease and Obesity but Decreases Risk of Alzheimer’s Disease and Myocardial Infarction. Hum Mol Genet. 2021 Apr 15;ddab096. [Online ahead of print] PMID: 33856023. https://doi.org/10.1093/hmg/ddab096
106. Natarajan P, Pampana A, Graham SE, Ruotsalainen SE, Perry JA, de Vries PS, Broome JG, Pirruccello JP, Honigberg MC, Aragam K, Wolford B, Brody JA, Antonacci-Fulton L, Arden M, Aslibekyan S, Assimes TL, Ballantyne CM, Bielak LF, Bis JC, Cade BE, Do R, Doddapaneni H, Emery LS, Hung Y-J, Irvin MR, Khan AT, Lange L, Lee J, Lemaitre RN, Martin LW, Metcalf G, Montasser ME, Moon J-Y, Muzny D, O’Connell JR, Palmer ND, Peralta JM, Peyser PA, Stilp AM, Tsai M, Wang FF, Weeks DE, Yanek LR, Wilson JG, Abecasis G, Arnett DK, Becker LC, Blangero J, Boerwinkle E, Bowden DW, et al. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. Nat Commun. 2021 Apr 12;12(1):2182. PMID: 33846329. https://doi.org/10.1038/s41467-021-22339-1
107. Macintyre AN, French MJ, Sanders BR, Riebe KJ, Shterev ID, Wiehe K, Hora B, Evangelous T, Dugan G, Bourland JD, Cline JM, Sempowski GD. Long-Term Recovery of the Adaptive Immune System in Rhesus Macaques After Total Body Irradiation. Adv Radiat Oncol. 2021 Apr 19;6(5):100677. PMCID: PMC8498734. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8498734/
108. Black-Schaffer WS, Robboy SJ, Gross DJ, Crawford JM, Johnson K, Austin M, Karcher DS, Johnson RL, Powell SZ, Sanfrancesco J, Cohen MB. Evidence-Based Alignment of Pathology Residency with Practice II: Findings and Implications. Acad Pathol. 2021 Apr 7;8:23742895211002816. (eCollection Jan-Dec 2021). PMCID: PMC8040604. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8040604/
109. Su J, *Song Q, Qasem S, O’Neill S, Lee J, Furdui CM, Pasche B, Metheny-Barlow L, Masters AH, Lo H-W, Xing F, Watabe K, Miller LD, Tatter SB, Laxton AW, Whitlow CT, Chan MD, Soike MH, Ruiz J. Multi-Omics Analysis of Brain Metastasis Outcomes Following Craniotomy. Front Oncol. 2021 Apr 6;10:615472. PMCID: PMC8056216. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8056216/
110. Bancks MP, Bertoni AG, Carnethon M, Chen H, Cotch MF, Gujral UP, Herrington D, Kanaya AM, Szklo M, Vaidya D, Kandula NR. Association of Diabetes Subgroups with Race/Ethnicity, Risk Factor Burden and Complications: the MASALA and MESA Studies. J Clin Endocrinol Metab. 2021 Apr 23;106(5):e2106-e2115. PMCID: PMC8063247 https://doi.org/10.1210/clinem/dgaa962
111. Kim S, Hsu F-C, Groban L, Williamson J, Messier S. A pilot study of aquatic prehabilitation in adults with knee osteoarthritis undergoing total knee arthroplasty – short term outcome. BMC Musculoskelet Disord. 2021 Apr 26;22(1):388. PMCID: PMC8074697. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8074697/
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113. Lipchick BC, Utley A, Han Z, Moparthy S, Yun DH, Bianchi-Smiraglia A, Wolff DW, Fink E, Liu L, Furdui CM, Lee J, Lee KP, Nikiforov MA. The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma. Blood Adv. 2021 Apr 13;5(7):1933-1946. PMCID: PMC8045499. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8045499/
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MAY 2021
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178. Reynolds LM, Zamora C, Lee UJ, Stokes AC, Benjamin EJ, Bhatnagar A, Payne TJ, Rodriguez CJ. Tobacco Use Prevalence and Transitions from 2013 to 2018 Among Adults with a History of Cardiovascular Disease. J Am Heart Assoc. 2021 Jun 15;10(12):e021118. PMID: 34102851. https://doi.org/10.1161/jaha.121.021118
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180. Bourgeois FT, Gutierrez-Sacristan A, Keller MS, Liu M, Hong C, Bonzel C-L, Tan ALM, Aronow BJ, Boeker M, Booth J, Cruz Rojo J, Devkota B, Garcia Barrio N, Gehlenborg N, Geva A, Hanauer DA, Hutch MR, Issitt RW, Klann JG, Luo Y, Mandl KD, Mao C, Moal B, Moshal KL, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Patel LP, Pedrera Jimenez M, Sebire NJ, Serrano Balazote P, Serret-Larmande A, South AM, Spiridou A, Taylor DM, Tippmann P, Visweswaran S, Weber GM, Kohane IS, Cai T, Avillach P, Consortium for Clinical Characterization of COVID-19 by HER (4CE). International Analysis of Electronic Health Records of Children and Youth Hospitalized with COVID-19 Infection in 6 Countries. JAMA Netw Open. 2021 Jun 1;4(6):e2112596. PMCID: PMC8196345. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8196345/
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185. Li W, Justice-Clark T, Cohen MB. The utility of ThyroSeq ® in the management of indeterminate thyroid nodules by fine-needle aspiration. Cytopathology. (Epub 2021 Apr 29). PMID: 33914382. https://doi.org/10.1111/cyt.12981
186. Shinn R, Park C, DeBose K, Hsu F-C, Cecere T, Rossmeisl J. Feasibility and accuracy of 3D printed patient-specific skull contoured brain biopsy guides. Vet Surg. 2021 Jul;50(5):933-943. (Epub 2021 May 10). PMCID: PMC8359966. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8359966/
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188. Botoseneanu A, Chen H, Ambrosius WT, Allore HG, Anton S, Folta SC, King AC, Nicklas BJ, Spring B, Strotmeyer ES, Gill TM. Metabolic syndrome and the benefit of a physical activity intervention on lower-extremity function: Results from a randomized clinical trial. Exp Gerontol. 2021 Jul 15;150:111343. (Epub 2021 Apr 10) PMID: 33848565. https://doi.org/10.1016/j.exger.2021.111343
189. Jatoi A, Ou F-S, Ahn DH, Zemla TJ, Le-Rademacher JG, Boland P, Ciombor KK, Jacobs NL, Pasche B, Cleary JM, McCune JS, Pedersen KS, Barzi A, Chiorean EG, Heying EN, Lenz H-J, Sloan JA, Grothey A, Lacouture ME, Bekaii-Saab T. Preemptive Versus Reactive Topical Clobetasol for Regorafenib-Induced Hand-Foot Reactions: A Preplanned Analysis of the ReDOS Trial. Oncologist. 2021 Jul;26(7):610-618. (Epub 2021 Mar 6) PMID: 33604969. https://doi.org/10.1002/onco.13730
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191. Drzeniek NM, Mazzocchi A, Schlickeiser S, Forsythe S, Moll G, Geissler S, Reinke P, Gossen M, Gorantla VS, Volk H-D, Soker S. Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells. Biofabrication. 2021 Jul 8;13(4). (Epub 2021 Jun 10). PMID: 34111862. https://doi.org/10.1088/1758-5090/ac0a32
192. Estave PM, Beeghly S, Anderson R, Margol C, Shakir M, George G, Berger A, O’Connell N, Burch R, Haas N, Powers SW, Seng E, Buse DC, Lipton RB, Wells RE. Learning the full impact of migraine through patient voices: A qualitative study. Headache. 2021 Jul;61(7):1004-1020. (Epub 2021 Jun 3). PMID: 34081779. https://doi.org/10.1111/head.14151
193. Case L, Adler-Neal AL, Wells RE, Zeidan F. The role of expectations and endogenous opioids in mindfulness-based relief of experimentally-induced acute pain. Psychosom Med. 2021 Jul-Aug 01;83(6):549-556. (Epub 2021 Jan 15). PMID: 33480666. https://doi.org/10.1097/psy.0000000000000908
194. Palmer ND, Kahali B, Kuppa A, Chen Y, Du X, Feitosa MF, Bielak LF, O’Connell JR, Musani SK, Guo X, Smith AV, Ryan KA, Eirksdottir G, Allison MA, Bowden DW, Budoff MH, Carr JJ, Chen Y-D I, Taylor KD, Correa A, Crudup BF, Halligan B, Yang J, Kardia SLR, Launer LJ, Fu Y-P, Mosley TH, Norris JM, Terry JG, O’Donnell CJ, Rotter JI, Wagenknecht LE, Gudnason V, Province MA, Peyser PA, Speliotes EK. Allelle-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer’s disease and myocardial infarction. Hum Mol Genet. 2021 Jul 9;30(15):1443-1456. PMCID: PMC8283205. https://doi.org/10.1093/hmg/ddab096
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196. Tessou KD, Lemus H, Hsu F-C, Pierce J, Hong S, Brown L, Wu T. Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors. Nutrients. 2021 Jul 15;13(7):2422. PMCID: PMC8308757. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8308757/
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198. Plair A, Evans RJ, Langefeld CD, Matthews CA, Badlani G, Walker SJ. Anesthetic Bladder Capacity is a Clinical Biomarker for Interstitial Cystitis/Bladder Pain Syndrome Subtypes. Urology. 2021 Jul 22;S0090-4295(21)00682-8. [Online ahead of print] PMID: 34303757. https://doi.org/10.1016/j.urology.2021.07.009
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200. Lee HC, Ailawadhi S, Gasparetto CJ, Jagannath S, Rifkin RM, Durie BGM, Narang M, Terebelo HR, Toomey K, Hardin JW, Wagner L, Omel JL, Dhalla M, Liu L, Joshi P, Abonour R, Connect MM Registry. Treatment patterns and outcomes in elderly patients with newly diagnosed multiple myeloma: results from the Connect ® MM Registry. Blood Cancer J. 2021 Jul 23;11(7):134. PMCID: PMC8302734. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8302734/
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226. Kittner SJ, Sekar P, *Comeau ME, Anderson CD, Parikh GY, Tavarez T, Flaherty ML, Testai FD, Frankel MR, James ML, Sung G, Elkind MSV, Worrall BB, Kidwell CS, Gonzales NR, Koch S, Hall CE, Birnbaum L, Mayson D, Coull B, Malkoff MD, Sheth KN, McCauley JL, Osborne J, Morgan M, Gilkerson La, Behymer TP, Demel SL, Moomaw CJ, Rosand R, Langefeld CD, Woo D. Ethnic and Racial Variation in Intracerebral Hemorrhage Risk Factors and Risk Factor Burden. JAMA Netw Open. 2021 Aug 2;4(8):e2121921. PMCID: PMC83831330. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8383133/
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228. Brinkley TE, Leng I, Bailey MJ, Houston DK, Hugenschmidt CE, Nicklas BJ, Hundley WG. Effects of Exercise and Weight Loss on Proximal Aortic Stiffness in Older Adults with Obesity. Circulation. 2021 Aug 31;144(9):684-693. (Epub 2021 Aug 2). PMCID: PMC8405553. https://doi.org/10.1161/circulationaha.120.051943
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230. Stem C, Rodman C, Ramamurthy RM, George S, Meares D, Farland A, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G. Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A. Front Cell Dev Biol. 2021 Aug 10;9:678117. PMCID: PMC8383113. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8383113/
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236. Ruiz J, Chan M, Strowd RE. Treatment of Leptomeningeal Metastases: New Hammer, the Same Nail. J Thorac Oncol. 2021 Aug;16(8):1244-1246. PMID: 34304852. https://doi.org/10.1016/j.jtho.2021.06.009
237. Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu S-Y, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo Y-Y, Shiozawa Y, Singh R, Watabe K. Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer. Nat Commun. 2021 Aug 31;12(1):5196. PMCID: PMC8408156. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8408156/
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SEPTEMBER 2021
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242. Pan X-F, Yang JJ, Shu X-O, Moore SC, Palmer ND, Guasch-Ferre M, Herrington DM, Harada S, Eliassen H, Wang TJ, Gerszten RE, Albanes D, Tzoulaki I, Karaman K, Elliott P, Zhu H, Wagenknecht LE, Zheng W, Cai H, Cai Q, Matthews CE, Menni C, Meyer KA, Lipworth LP, Ose J, Fornage M, Ulrich CM, Yu D. Associations of circulating choline and its related metabolites with cardiometabolic biomarkers: an international pooled analysis. Am J Clin Nutr. 2021 Sep 1;114(3):893-906. (Epub 2021 May 21) PMCID: PMC8408854. https://doi.org/10.1093/ajcn/nqab152
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251. Kho AT, McGeachie MJ, Li J, Chase RP, Amr SS, Hastie AT, Hawkins GA, Li X, Chupp GL, Meyers DA, Bleecker ER, Weiss ST, Tantisira KG. Lung function, airway and peripheral basophils and eosinophils are associated with molecular pharmacogenomics endotypes of steroid response in severe asthma. Thorax. 2021 Sep;thoraxjnl-2020-215523. (Online ahead of print) PMID: 34580195. https://doi.org/10.1136/thoraxjnl-2020-215523
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255. Sanders S, Herpai DM, Rodriguez A, Huang Y, Chou J, Hsu F-C, Seals D, Mott R, Miller LD, Debinski W. The Presence and Potential Role of ALDH1A2. In the Glioblastoma Microenvironment. Cells. 2021 Sep 20;10(9):2485. PMCID: PMC8468822. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8468822/
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257. Mangieri CW, Valenzuela CD, Erali RA, Votanopoulos K, Shen P, Levine EA. ASO Visual Abstract: Incidence, Risk Factors, and Outcomes from Conversion of Low-Grade to High-Grade Appendiceal Neoplasms for Patients Undergoing Multiple Cytoreductive Surgeries with Hyperthermic Intraperitoneal Chemotherapy. Ann Surg Oncol. 2021 Sep 3. (Online ahead of print). PMID: 34480281. https://doi.org/10.1245/s10434-021-10737-0
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261. Schulson L, Lin M-Y, Paasche-Orlow MK, Hanchate AD. Limited English Proficient Patient Visits and Emergency Department Admission Rates for Ambulatory Care Sensitive Conditions in California: A Retrospective Cohort Study. J Gen Intern Med. 2021 Sep;36(9):2683-2691. PMCID: PMC8390610. https://doi.org/10.1007/s11606-020-06523-5
262. Sohl SJ, Befus D, Tooze JA, Levine B, Golden SL, Puccinelli-Ortega N, Pasche BC, Weaver KE, Lich KH. Feasibility of Systems Support Mapping to guide patient-driven health self-management in colorectal cancer survivors. Psychol Health. 2021 Sep 27;1-21. (Online ahead of print) PMID: 34570677. https://doi.org/10.1080/08870446.2021.1979549
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OCTOBER 2021
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272. Mora DC, Sandberg JC, Howard TD, Hsu F-C, Quandt SA, Arcury TA. Genetic Knowledge and Communication Among Mexican Farmworkers and Non-farmworkers in North Carolina. J Immigr Minor Health. 2021 Oct;23(5):1026-1034. (Epub 2021 Jan 19). PMID: 33469784. https://doi.org/10.1007/s10903-020-01136-w
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