Announcements

NIH Funding Opportunities: https://grants.nih.gov/grants/guide/WeeklyIndexMobile.cfm?utm_source=Master+Research+Rundown+%26+Funding&utm_campaign=0f0fe13edf-EMAIL_CAMPAIGN_2020_04_14_08_58_COPY_01&utm_medium=email&utm_term=0_9d8dbeb58a-0f0fe13edf-194798127

Misc Funding Opportunites: https://mailchi.mp/wakehealth.edu/8yng942go6-8247862?e=9122ea0f40

Upcoming Events

Final PhD Defense for Angelica Riojas – MMTS Graduate Program Date/Time:     Wednesday, Aug 25th (1:00pm) Title:                “Renal Genetic Variation Underlying Blood Pressure Regulation in Female Primates” Webex:           https://wakehealth.webex.com/wakehealth/j.php?MTID=mc7e2f913c411e938540e2cc0d01d4101 Meeting #: 161 674 9535 Passcode: AzMj5g2bbU4

Comparative Medicine Research Strategy Meeting Date/Time:     Tuesday, Aug 31st (3:30 – 4:30pm) Speaker:         Matthew Jorgensen, PhD (Associate Professor – Comparative Medicine) Title:               “Vervet Research Colony Update & Possible P40 Supplements” Webex:           https://wakehealth.webex.com/wakehealth/j.php?MTID=mc5fa69473e20b15b3c5139bbe04f59b2 Meeting #: 1619 69 8484 Passcode:  ZNmyyAYR634

SAVE THE DATE – Hazzard Symposium: Cellular Bioenergetics Friday, November 5th  8:00am – 3:00pm Details and schedule to follow

Recent Publications

Seplyarskiy VB, Soldatov RA, Koch E, McGinty RJ, Goldmann JM, Hernandez RD, Barnes K, Correa A, Burchard EG, Ellinor PT, McGarvey ST, Mitchell BD, Vasan RS, Redline S, Silverman E, Weiss ST, Arnestt DK, Blangero J, Boerwinkle E, He J, Montgomery C, Rao DC, Rotter JI, Taylor KD, Brody JA, Chen Y-D I, de Las Fuentes L, Hwu C-M, Rich SS, Manichaikul AW, Mychaleckyj JC, Palmer ND, et. al. Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021 Aug 12;eaba7408. (Online ahead of print) PMID: 34385354. https://doi.org/10.1126/science.aba7408 

Lomas-Soria C, Cox LA, Nathanielsz PW, Zambrano E. Sexual dimorphism in liver cell cycle and senescence signaling pathways in young and old rats. J Physiol. 2021 Aug 13. (Online ahead of print) PMID: 34387378. https://doi.org/10.1113/jp281822  

Wang X, Zhou X, Uberseder B, Lee J, Latimer CS, Furdui CM, Keene CD, Montine TJ, Register TC, Craft S, Shively CA, Ma T. Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer’s disease. Neurobiol Dis. 2021 Aug 4;158:105463. (Online ahead of print) PMID: 34363967. https://doi.org/10.1016/j.nbd.2021.105463 

Tavolara TE, Gurcan MN, Segal S, Niazi MKK. Identification of difficult to intubate patients from frontal face images using an ensemble of deep learning models. Comput Biol Med. 2021 Aug 4;136:104737. PMID: 34391000. https://doi.org/10.1016/j.compbiomed.2021.104737 

Johnson CS, Shively C, Michaelson KT, Lea AJ, DeBo RJ, Howard TD, Hawkins GA, Appt SE, Liu Y, McCall CE, Herrington DM, Ip EH, Register TC, Snyder-Mackler N. Contrasting effects of Western vx. Mediterranean diets on monocyte inflammatory gene expression and social behavior in a primate model. Elife. 2021 Aug 2;10:e68293. (Online ahead of print) PMID: 34338633. https://doi.org/10.7554/elife.68293 

Members NEWS

Dr. Roy E. Strowd had a recent press release by the American Academy of Neurology “Could Ketogenic Diet be Helpful with Brain Cancer?”  “There are not a lot of effective treatments for these types of brain tumors, and survival rates are low, so any new advances are very welcome,” said study author Roy E. Strowd, MD, MS, MEd, of Wake Forest School of Medicine in Winston-Salem, N.C., and a Fellow of the American Academy of Neurology. “These cancer cells rely on glucose, or sugar, to divide and grow. Since the ketogenic diet is low in sugar, the body changes what it uses for energy—instead of carbohydrates, it uses what are called ketones. Normal brain cells can survive on ketones, but the theory is that cancer cells cannot use ketones for energy.” For the full release: https://www.aan.com/PressRoom/Home/PressRelease/4907