Announcements
Congratulations: Dr. Genesio Karere – Assistant Professor in Molecular Medicine Dr. Karere has be invited to serve as a Member on the ATVB Diversity Committee of the Council on Arteriosclerosis, Thrombosis and Vascular Biology from 2020 – 2022
Wake Forest Alzheimer’s Disease Research Center – Request for Applications for Development Projects and Pilot Grant Awards WF ADRC is seeking proposals for projects to stimulate new and innovative research relevant to Alzheimer’s disease. The primary focus of this funding is the development of research focused on AD that will lead to publications and extramural research applications, or produce resources useful to the WF ADRC community. The scientific theme of the WF ADRC is the link between metabolic and vascular diseases and the transitions from normal aging to mild cognitive impairment AD, and related disorders. Research that addresses health disparities in AD is also a goal. Projects can be basic, translational, or clinical research, and can encompass biomedical, epidemiological, caregiving, educational, or behavioral research. Development Projects – up to $50,000 for the first year with a consideration for a second year of funding. Pilot Grants – up to $20,000 in funding for one year with up to 5% of direct costs usable for PI effort support. Letters of Intent – Due by November 6th - Invitations November 13th - Full Applications due by January 29th See attachment for complete information.
NIH Funding Opportunities https://grants.nih.gov/grants/guide/WeeklyIndexMobile.cfm
Foundation Funding Opportunities https://ctsi.wakehealth.edu/-/media/WakeForest/CTSI/Files/Funding-Opportunities/NIH-Funding-Opportunities.pdf
Upcoming Events
Breast Cancer Center of Excellence (BCCOE) – Hosting Webex Date/Time: Monday, Oct 19th – 12:00pm – 1:00pm Presenter: Bethany A Kerr, PhD (Assistant Professor in Cancer Biology, WFSOM) Talk Title: “Generating Clinically-Relevant Breast Cancer Metastatic Models” Webex Info: Meeting #: 171 785 2850 Password: BJdAj3ybn23 Link: Join meeting
Implementation Science Affinity Group – Presents a Science Speaker Event Date/Time: Wednesday, Oct 21st – 12:00pm – 1:00pm Presenter: Sarah A. Birken, PhD (Associate Professor, Implementation Science – WFSOM) Talk Title: “Organizational Perspectives and Theories for Implementation Science’ Registration: Register to receive Webex information. https://redcap.wakehealth.edu/redcap/surveys/?s=A7PNN3C73L
Diagenode Series - Epigenetics Webinar Date/Time: Thursday, Oct 22nd – 2pm Presenter: Swapan Das, M.Sc, PhD (Assistant Professor, Endocrinology & Metabolism, WFSOM) Talk Title: “Adipose Tissue DNA Methylation and Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity” Webex Info: (registration required) Register now [diagenode.us18.list-manage.com]
Molecular Medicine Journal Club (MMTS 781) – Webex Date/Time: Friday, Oct 23rd – 12:15pm – 1:15pm Presenter: Ellen Quillen, PhD Assistant Professor, Molecular Medicine Paper Title: “A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos” The American Journal of Human Genetics (2020), https://doi.org/10.1016/j.ajhg.2020.09.003 WebEx Info: Meeting #: 171 652 6202 Meeting password: xH9JDQsMH33
RCCN and the National Institute on Aging presents : Webinar Date/Time: Friday, Oct 23rd – 12-1pm Presenter: Dr. Shantanu Singh Senior Group Leader in the Imaging Platform at the Broad Institute Talk Title: “Accelerating Drug Discovery through the Power of Cell Morphology” Info: For complete information and to register – https://us02web.zoom.us/webinar/register/WN_vm4DICa-Qi6Qvd4JKAtyIw
Recent Publications
Miller-Ocuin JL, Howard-McNatt M, Levine EA, Chiba A. Is Sentinel Lymph Node Biopsy Necessary for Ductal Carcinoma in Situ Patients Undergoing Mastectomy? Am Surg. 2020 Aug 29;3134820942164. [Online ahead of print] PMID: 32862671. https://doi.org/10.1177/0003134820942164
Haung RSP, Li X, Haberberger J, Sokol E, Severson E, Duncan DL, Hemmerich A, Edgerly C, Williams E, Elvin J, Vergilio J-A, Killian JK, Lin D, Hiemenz M, Xiao J, McEwan D, Holmes O, Danziger N, Erlich R, Frampton G, Cohen MB, McGregor K, Reddy P, Cardeiro D, Anhorn R, Venstrom J, Alexander B, Brown C, Pusztai L, Ross JS, Ramkissoon SH. Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer. Oncologist. 2020 Sep 1. [Online ahead of print] PMID: 32869930. https://doi.org/10.1634/theoncologist.2020-0449
Ahn YJ, *Wang L, *Foster S, Asmis R. Dietary 23-Hydroxy Ursolic Acid Protects Against Diet-Induced Weight Gain and Hyperglycemia by Protecting Monocytes and Macrophages Against Nutrient Stress-Triggered Reprogramming and Dysfunction and Preventing Adipose Tissue Inflammation. J Nutr Biochem. 2020 Aug 26;108483. [Online ahead of print] PMID: 32860922. https://doi.org/10.1016/j.jnutbio.2020.108483
Ghoshal S, Allred ND, Freedman BI. The Contribution of Kidney Disease to Cognitive Impairment in Patients with Type 2 Diabetes. Review > Curr Diab Rep. 2020 Aug 28;20(10):49. PMID: 32857243. https://doi.org/10.1007/s11892-020-01333-9
Hassan MS, Pullikuth A, Nelson KC, Flores A, Karpova Y, Baiz D, Zhu S, Sui G, Huang Y, D’Agostino R, *Hemal A, von Holzen U, Debinski W, Kulik G. Beta2-adrenoreceptor signaling increases therapy-resistance in prostate cancer by upregulating MCL1. Mol Cancer Res. 2020 Sep 14;molcanres.1037.2019. PMID: 32928910. https://doi.org/10.1158/1541-7786.mcr-19-1037
*indicates an author who is affiliated in the highlighted member’s lab
Member Highlights
2020 Research Awards Announced!!!!!
Established Investigator in Basic/Translational Science
J. Mark Cline, DVM, PhD (Professor, Patholgy-Comparative Medicine)
Established Investigator in Clinical/Population Science
Carl D. Langefeld, PhD (Professor, Biostatistics & Data Science)
Mentoring Award
John S. Parks, PhD (Professor, Molecular Medicine)
Barbara Nicklas, PhD (Professor, Gerontology & Geriatric Medicine)
Mid-Career Investigator in Basic/Translational Science
Gagan Deep, PhD (Associate Professor, Cancer Biology)
Leah Solberg Woods, PhD (Associate Professor, Molecular Medicine)