Announcements
Comprehensive Cancer Center – Request for Applications for Pilot Awards Cancer Genetics and Metabolism Program PUSH Pilot Info: The pilot awards will be used to fund research relevant to the scientific aims of the Program, which are to 1) characterize the deregulated cancer genome; 2) interrogate cancer metabolic alterations; and 3) translate knowledge from aims 1 and 2 to screening, diagnosis, and novel therapeutic approaches. The goal of the “PUSH” pilot grant is to catalyze new and innovative ideas that allow investigators to pursue a line of research with a high likelihood for extramural funding. The CCC will fund up to $100,000 in direct costs per project. Link for complete information: file:///C:/Users/grpate/Downloads/2020%20Comprehensive%20Cancer%20Center%20CCC%20Cancer%20Genetics%20and%20Metabolism%20CGM%20Program%20%20RFA%20(1).pdf Deadline: Dec 16th Full Applications due. https://redcap.wakehealth.edu/redcap/surveys/?s=3T8WRX93MK
Wake Forest Center for Biomedical Informatics: Request for Application for Pilot Awards Info: WFBMI is seeking proposals for innovative and translational informatics solutions to healthcare and biomedical research problems. Novel technologies, including but not limited to, testing the feasibility of novel approaches as well as unconventional solutions to translational research problems by leveraging one or more informatics tools and methods are highly encouraged. Two projects will be funded up to $25,000 each, to be spent within a 12-month project period. Link for complete information: https://ctsi.wakehealth.edu/-/media/WakeForest/CTSI/Files/Funding-Opportunities/2020/Common-Deadline-2020/2020-WF-Center-for-Biomedical-Informatics-RFA.pdf Deadline: Dec 16th Full Applications due. https://redcap.wakehealth.edu/redcap/surveys/?s=Y3F4994P8R
Foundation Funding Opportunities: https://ctsi.wakehealth.edu/-/media/WakeForest/CTSI/Files/Funding-Opportunities/NIH-Funding-Opportunities.pdf
NIH Funding Opportunities: https://grants.nih.gov/grants/guide/WeeklyIndexMobile.cfm
Internal Pilot Award Funding Opportunities: https://ctsi.wakehealth.edu/Funding-Opportunities?utm_source=Master+Research+Rundown+%26+Funding&utm_campaign=b6d576989e-EMAIL_CAMPAIGN_2020_11_02&utm_medium=email&utm_term=0_9d8dbeb58a-b6d576989e-194798127
Upcoming Events
2020 William R. Hazzard, MD Translational Research in Aging Virtual Symposium The Hazzard Symposium is an annual event at Wake Forest School of Medicine which features internationally-renowned speakers in gerontology and geriatric medicine with the purpose of translating discoveries in aging research to the care of older adults. The topic for this year’s Symposium is “COVID-19 and Older Adults.” Themes of the Symposium include: Geroscience Approaches; Population Impact; and Telehealth Applications During COVID-19. (See attached agenda) Date/Time: Friday, November 13th - 10:00am – 3:00pm Presenters: Stephen B. Kritchevsky, PhD William R. Hazzard, MD Christopher Ohl, MD Joan Mannick, MD, CEO, resTORbio (Keynote) John Sanders, MD, MPH David Herrington, MD, PhD James Kirkland, MD, PhD Jantira Thomas, DO Bonnie Sachs, PhD Steve Rapp, PhD Peggy Cawthon, PhD, MPH Nir Barzilai, MD Registration is FREE but required: https://us02web.zoom.us/webinar/register/WN_wtDQlOivRciS89HqIS-jWw [us02web.zoom.us]
Center for Redox Biology and Medicine Seminar – Webex Date/Time: Tuesday, Nov 10th – 11:00am – 12:00pm Presenter: Dr. Rakesh P. Patel Professor and Vice Chair for Research, Department of Pathology Director, Center for Free Radical Biology University of Alabama at Birmingham Talk Title: “Redox-Dependent Regulation of the Endothelial ‘N-Glycoform Zipcode’: Implications for Vascular Inflammation” WebEx Info: https://wakehealth.webex.com/wakehealth/onstage/g.php?MTID=ea21a84e14a2da7f6abba5caa2c56ac9f
Ø Aging Center Journal Club – Webex Date/Time: Wednesday, Nov 11th – 1:00pm – 2:00pm Articles for Presentation: Dr. Julia Provchy “Healthy lifestyle and the risk of Alzheimer dementia: Findings from 2 longitudinal studies” https://n.neurology.org/content/95/4/e374.long Dr. Katherine Hsieh “Different Combinations of Mobility Metrics Derived from a Wearable Sensor are Associated with Distinct Health Outcomes in Older Adults” https://academic.oup.com/biomedgerontology/article/75/6/1176/5524130 Round Robin Article: Dr. Caitlin Jones “Preoperative depressive symptoms associated with poor functional recovery after surgery” https://onlinelibrary.wiley.com/doi/epdf/10.1111/jgs.16781 Webex info: Join meeting Meeting #: 178 834 6668 Password: pbYYdb38MT8
Biochemistry Seminar Series – Webex Date/Time: Thursday, Nov 12th – 2:00pm – 3:00pm Presenter: Dr. Shaun Olsen Associate Professor UT Health San Antonio Talk Title: “DNA Repair Mechanisms” WebEx Info: https://wakehealth.webex.com/wakehealth/j.php?MTID=m42dadd0731e40ebd38c67eb821b2cd62 Password: wake
Molecular Medicine Journal Club (MMTS 781) – Webex Date/Time: Friday, Nov 13th – 12:15pm – 1:15pm Presenter: Ravichandra Vemuri, PhD Postdoctoral Research Fellow Mentor: Kylie Kavanagh, VMS Dept: Comparative Medicine Talk title: “Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes” Gut. 2020 Oct;69(10):1796-1806. https://gut.bmj.com/content/69/10/1796 WebEx Info: Meeting #: 171 652 6202 Meeting password: xH9JDQsMH33 Join meeting [wakehealth.webex.com]
Recent Publications
Gibbs K, Chuang Key C-C, Belfied L, Krall J, Purcell L, Liu C, Files DC. “Aging Influences the Metabolic and Inflammatory Phenotype in an Experimental Mouse Model of Acute Lung Injury” J Gerontol A Biol Sci Med Sci. 2020 Sep 30;glaa248. [Online ahead of print.] PMID: 32997738. https://doi.org/10.1093/gerona/glaa248
Ejike CO, Woo H, Galiatsatos P, Paulin LM, Krishnan JA, Cooper CB, Couper DJ, Kanner RE, Bowler RP, Hoffman EA, Comellas AP, Criner GJ, Barr RG, Martinez FJ, Han MK, Martinez CH, Ortega VE, Parekh TM, Christenson SA, Thakur N, Baugh A, Belz DC, Raju S, Gassett AJ, Kaufman JD, Putcha N, Hansel NN. Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes. Am J Respir Crit Care Med. 2020 Oct 2. [Online ahead of print] PMID: 33007162. https://doi.org/10.1164/rccm.202002-0253oc
Snider AJ, Seeds MC, Johnstone L, Snider JM, Hallmark RD, Franco CM, Parks JS, Bensen JT, Broeckling CD, Mohler JL, Smith GJ, Fontham ETH, Lin H-K, Bresette W, Sergeant S, Chilton FH. Identification of Plasma Glycosphingolipids as Potential Biomarkers for Prostate Cancer (Pca) Status. Biomolecules. 2020. Sep 30;10(10):E1393. PMID: 33007922. https://doi.org/10.3390/biom10101393
Sagar R, Almeida-Porada G, Blakemore K, Chan JK, Choolani M, Gotherstrom C, Jaulent A, MacKenzie TC, Mattar C, Porada CD, Peranteau WH, Schneider H, Shaw SW, Waddington SN, Westgren M, David AL. Fetal and maternal safety considerations for in utero therapy clinical trials: iFeTiS consensus statement. Mol Ther. 2020 Oct 15;S1525-0016(20)30546-3. [Online ahead of print] PMID: 33069884. https://doi.org/10.1016/j.ymthe.2020.10.012
Anderson WD, Soh JY, Innis SE, Dimanche A, Ma L, Langefeld CD, *Comeau ME, Das SK, Schadt EE, Björkegren JLM, Civelek M. Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis. Genome Res. 2020 Oct;30(10):1379-1392. PMID: 32967914. https://doi.org/10.1101/gr.264614.120
*Dosso B, Waits CMK, Simms KN, Sergeant S, Files DC, Howard TD, Langefeld CD, Chilton FH, Rahbar E. Impact of rs174537 on Critically Ill Patients with Acute Lung Injury: A Secondary Analysis of the OMEGA Randomized Clinical Trial. Curr Dev Nutr. 2020 Sep 14;4(10):nzaa147. PMCID: PMC7524639. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7524639/
*indicates an author who is affiliated in the highlighted member’s lab
Member Highlights
35th Annual Medical Student Research Day (MSRD) – Poster Awards · T1 Translational Science Research Award Rachel Jeffries (2023) – Mentor: Mathew Quinn, PhD Poster Title: Evaluating the Effects of Advanced Maternal Age on Offspring Body Weight and Lipid Profiles in Nonhuman Primates. Meredith Award for Outstanding Health Equity Research Alexandria Marshal (2023) – Mentor: Roy Strowd, Med, MD Poster Title: Defining Personal & Communal Aspects of Social Determinants of Health Glioma Patients.