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Brett Marie Frye

Research Fellow for Comparative Medicine/Pathology

Mentor(s): Dr. Carol Shively 

Brett uses a life course perspective to investigate how environmental factors interact to shape health trajectories. She has worked with several nonhuman primate (NHP) models of human health, including marmosets, cynomolgus monkeys, and vervets. Previously, Brett explored how antenatal environments influenced reproductive, health, and survival outcomes in marmosets, an important model for maternal programming and neuroscience. Recently, Brett pivoted from examining early- to late windows of sensitivity. Her current projects encompass two complementary aims: 1) to investigate the effects of Mediterranean versus Western diets on physical function and metabolic perturbations that increase Alzheimer’s disease (AD) risk and 2) to develop vervets as a NHP model of neurodegeneration and cognitive decline that also is relevant to understanding the etiopathology of AD. Brett hopes this comprehensive, integrative approach will help clarify the mechanisms underlying divergent aging trajectories and inspire interventions that increase resilience to age-related conditions.

 


Manuel Izquierdo, DO

Research Fellow – Pulmonary Disease Critical Care Medicine

Mentor(s): Dr. Victor Ortega & Dr. Chad Marion

Manuel is from Greenville, SC. He did his residency at Eastern Carolina University in Greenville, NC at the Brody School of Medicine in 2019.  He received his Doctor of Osteopathic Medicine (DO) at Edward Via College of Osteopathic Medicine – Virginia campus in 2015. He is currently a first year fellow in Wake Forest Pulmonary Disease and Critical Care Medicine unit working under Dr. Victor Ortega and Dr. Chand Marion.  Manuel really enjoys family time and rock climbing.


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Taeseok Oh, PhD

Research Fellow – Pathology – Comparative Medicine

Mentor(s): Dr. Matthew Quinn 

Taeseok received his BS (2010) and MS (2012) degrees from the department of Biotechnology at Daegu University in South Korea. He earned his PhD from Brain and Cognitive Sciences at Daegu Gyeongbuk Institute of Science and Technology in 2018.